Uncovering Nutritional Support Strategies for Effective Management of Dry Age-Related Macular Degeneration
As seasoned optometrists, we frequently encounter inquiries from patients seeking effective ways to safeguard or enhance their vision, particularly when addressing age-related concerns such as macular degeneration. The importance of nutrition and supplementation in preserving optimal eye health cannot be emphasised enough, and an expanding body of clinical research underscores their critical role in managing dry age-related macular degeneration (AMD).
In this comprehensive evaluation, we will compare two prominent products available in the Australian market: Macutec Once Daily and Blackmores Macu-Vision Plus.

Grasping the Fundamentals of Macular Degeneration
Macular degeneration is a progressive condition that significantly impacts the macula, the central segment of the retina responsible for delivering clear, high-resolution vision. This condition ranks among the primary causes of severe vision loss in Australia, affecting thousands of individuals each year.
There are two main types of macular degeneration:
- Dry Macular Degeneration
This is the more prevalent form, accounting for approximately 90% of all cases. It entails a gradual thinning of the macular tissue, resulting in a slow but steady deterioration of central vision over time. - Wet Macular Degeneration
This variant is less common but considerably more severe. It arises when abnormal blood vessels develop and leak fluid or blood beneath the macula, frequently leading to sudden, irreversible vision loss if not addressed promptly.
What Are the Consequences of Failing to Treat Macular Degeneration Effectively?
- Dry AMD may progress gradually, but if ignored, it can result in significant vision loss over an extended period.
- Wet AMD necessitates immediate medical attention to avert permanent damage to central vision.
What Are the Standard Treatment Approaches for Macular Degeneration?
- Wet AMD is typically addressed through injections aimed at halting the growth of leaky blood vessels.
- Dry AMD is managed through a combination of lifestyle modifications and nutritional supplements that adhere to the scientifically validated AREDS2 formula.
Why Is Strict Adherence to the AREDS2 Formula Essential for Treatment?
The Age-Related Eye Disease Studies (AREDS and AREDS2) have transformed our insight into how nutritional support can be vital in combating AMD. The second study, AREDS2, fine-tuned the supplement composition by:
- Eliminating beta-carotene, which has been associated with an increased risk of lung cancer in smokers.
- Modifying zinc levels to ensure safer yet equally effective dosages.
- Incorporating lutein and zeaxanthin, two crucial macular carotenoids.
The outcome? A safer and more effective strategy for decelerating the advancement of dry AMD.


Which Supplements Meet AREDS2 Guidelines in Australia?
Two well-known supplement options that comply with these standards are:
1. Macutec Once Daily (by Stiltec – Proudly Australian Made)
Key Ingredients That Align with AREDS2 Guidelines:
- Vitamin C – 500mg
- Vitamin E – 400 IU
- Zinc Oxide – 25mg
- Copper – 2mg
- Lutein – 10mg
- Zeaxanthin – 2mg
Recommended dosage: One tablet daily with food.
Fully adheres to the AREDS2 formula
2. Blackmores Macu-Vision Plus
- Vitamin C – 250mg
- Vitamin E – 200 IU
- Zinc Oxide – 40mg
- Copper – 1mg
- Lutein – 5mg
- Zeaxanthin – 1mg
Recommended dosage: One tablet daily with food.
Contains only half the recommended dose of lutein and zeaxanthin according to AREDS2
What Are the Drawbacks of the Original Blackmores Macu-Vision?
This product lacks both lutein and zeaxanthin and does not comply with AREDS2 guidelines in any form. While it offers some antioxidant support, it fails to deliver the essential nutrients needed for maintaining optimal macular health.
Comparative Evaluation: Macutec versus Macu-Vision Plus
| Ingredient | Macutec Once Daily | Macu-Vision Plus | AREDS2 Recommended Dosage |
|---|---|---|---|
| Vitamin C | 500 mg | 250 mg | 500 mg |
| Vitamin E | 400 IU (as dl-alpha tocopheryl acetate) | 200 IU | 400 IU |
| Zinc (as Zinc Oxide) | 25 mg | 40 mg | 80 mg* |
| Copper (as Cupric Oxide) | 2 mg | 1 mg | 2 mg |
| Lutein | 10 mg (FloraGLO® Lutein) | 5 mg | 10 mg |
| Zeaxanthin | 2 mg (Optisharp® Zeaxanthin) | 1 mg | 2 mg |
| Capsules per day | 1 softgel | 1 tablet | 1 dose |
| AREDS2 Formula Compliance | Full Match |
Partial (half dose L/Z, low C/E) |
Based on NEI AREDS2 Formula |
*AREDS2 research indicated that lower zinc doses (25 mg) were equally effective and led to fewer side effects compared to higher amounts of 80 mg.
Ingredient Examination and Insights:
- Lutein & Zeaxanthin: Macutec Once Daily precisely adheres to the AREDS2 recommendation (10mg Lutein, 2mg Zeaxanthin), while Blackmores Macu-Vision Plus only provides half.
- Zinc: While Macutec employs a lower dosage of 25 mg Zinc, AREDS2 findings demonstrated that this quantity was equally effective and linked to fewer side effects compared to higher levels.
- Vitamin E Formulation: Macutec utilises dl-alpha tocopherol; although AREDS2 used natural d-alpha, this form is a widely accepted alternative that does not significantly affect most users.
- Manufacturing Standards: Macutec is Australian-made under pharmaceutical GMP and incorporates premium branded lutein (FloraGLO®) and zeaxanthin (Optisharp®), both of which were utilised in the original AREDS2 trials.
Key Considerations for Supplement Selection:
Macutec is also Australian-made, featuring branded carotenoids of high quality that are part of the AREDS2 study, designed for easy once-per-day dosing.
Macutec Once Daily offers a precise alignment with the AREDS2 formula, containing full-strength lutein (10 mg) and zeaxanthin (2 mg), while minimising excessive zinc intake.
Macu-Vision Plus, although promoted as an AREDS-style supplement, provides only half of the recommended L/Z dosage, lower antioxidant levels, and excess zinc that may be unwarranted.
Final Decision: Which Supplement Best Suits Your Needs?
Both supplements aim to slow the progression of dry macular degeneration, but only one fully adheres to the AREDS2 formula: Macutec Essentials. It provides:
- Full-strength, evidence-based ingredients
- Clinically validated effectiveness
- Exceptional value and accurate dosing
- Manufactured in Australia to high-quality standards
For these compelling reasons, Eyes by Design exclusively stocks Macutec Essentials, which we wholeheartedly recommend to our patients on the Central Coast and beyond.
Available in-store or for delivery throughout Australia.
Seeking Expert Eye Health Guidance?
If you have inquiries regarding macular health, nutritional supplements, or your eligibility for nutritional treatments, please do not hesitate to reach out to our knowledgeable team.
We provide personalised, expert advice rooted in the latest clinical research.
Call (02) 4369 8169
Visit us at Shop 6, Kincumber Centre, 39 Avoca Drive, Kincumber NSW 2251
Frequently Asked Questions About Macutec Once Daily Versus Macu-Vision Plus
What Is the AREDS2 Formula and Why Is It Vital for Eye Health?
AREDS2 represents a clinically validated combination of vitamins and minerals proven to decelerate the progression of dry age-related macular degeneration. This formula includes vitamin C, vitamin E, zinc, copper, lutein, and zeaxanthin. Supplements that conform to this formula, such as Macutec Essentials, offer the most evidence-backed protection for maintaining macular health.
What Is the Role of Macutec Once Daily in Eye Care?
Macutec Once Daily is specifically formulated to support eye health in individuals diagnosed with dry age-related macular degeneration. It is based on findings from the AREDS2 clinical research and aims to decelerate the progression of the disease by protecting the macula from oxidative damage.
Can Supplements Like Macutec or Macu-Vision Cure Macular Degeneration?
No, these supplements cannot cure the condition. However, they can significantly slow the progression of dry macular degeneration and may aid in preserving vision for a longer time. Early intervention and consistent usage are critical factors in achieving optimal results.
What Sets Macutec Once Daily Apart from Other Macular Supplements?
Macutec Once Daily includes all the validated AREDS2 components in a convenient once-daily capsule format. It utilises high-quality lutein and zeaxanthin identical to those used in clinical trials and is produced in Australia following strict pharmaceutical Good Manufacturing Practice standards.
How Do Lutein and Zeaxanthin Contribute to Overall Macular Health?
Lutein and zeaxanthin are natural pigments found within the macula. They play a significant role in forming the macular pigment, and sufficient intake is correlated with increased macular pigment density. This enhancement assists in filtering harmful blue light and safeguarding retinal tissue from oxidative stress.
Which Supplement Is Most Suitable If I Already Have Advanced Dry Macular Degeneration?
Macutec Once Daily is the optimal selection if you are in search of an AREDS2-compliant supplement that contains full-strength ingredients. It is specifically designed for patients diagnosed with moderate to advanced dry AMD who wish to slow its progression.
Citation
The insights and conclusions presented in this content are derived from the findings of the Age-Related Eye Disease Study 2 (AREDS2), conducted by the National Eye Institute, part of the National Institutes of Health. This study provides a comprehensive evaluation of the effectiveness of the AREDS2 supplement formulation in slowing the progression of age-related macular degeneration.
For additional information, please consult the National Eye Institute’s publication concerning the AREDS2 study.
In-Depth Comparison: Macu-Vision Plus vs Macutec Once Daily for Macular Degeneration Management
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